Search results for "genetics [Mutation]"

showing 10 items of 3026 documents

Plasmodium relictum infection and MHC diversity in the house sparrow (Passer domesticus).

2010

Antagonistic coevolution between hosts and parasites has been proposed as a mechanism maintaining genetic diversity in both host and parasite populations. In particular, the high level of genetic diversity usually observed at the major histocompatibility complex (MHC) is generally thought to be maintained by parasite-driven selection. Among the possible ways through which parasites can maintain MHC diversity, diversifying selection has received relatively less attention. This hypothesis is based on the idea that parasites exert spatially variable selection pressures because of heterogeneity in parasite genetic structure, abundance or virulence. Variable selection pressures should select for…

0106 biological sciencesPlasmodium[ SDV.IMM.IA ] Life Sciences [q-bio]/Immunology/Adaptive immunology01 natural sciencessusceptibilityMajor Histocompatibility Complex[ SDE ] Environmental SciencesGene Frequency[ SDV.EE.IEO ] Life Sciences [q-bio]/Ecology environment/SymbiosisResearch ArticlesGeneral Environmental ScienceGenetics0303 health sciencesbiologyPlasmodium relictumGeneral Medicine3. Good health[SDV.IMM.IA]Life Sciences [q-bio]/Immunology/Adaptive immunologyGenetic structure[SDE]Environmental Sciencesavian malariaGeneral Agricultural and Biological SciencesSparrowsMalaria AvianAntagonistic CoevolutionMajor histocompatibility complex010603 evolutionary biologyGeneral Biochemistry Genetics and Molecular Biologyresistance03 medical and health sciencesAvian malariamedicinePasser domesticusAnimalsSelection GeneticAllelesSelection (genetic algorithm)030304 developmental biologyLocal adaptationGenetic diversity[ SDE.BE ] Environmental Sciences/Biodiversity and EcologyGeneral Immunology and Microbiologydiversifying selectionbiology.organism_classificationmedicine.diseaseImmunity InnatePlasmodium relictumbiology.protein[SDE.BE]Environmental Sciences/Biodiversity and Ecology[SDV.EE.IEO]Life Sciences [q-bio]/Ecology environment/Symbiosis
researchProduct

Detection of Allee effects in marine fishes: analytical biases generated by data availability and model selection

2017

The demographic Allee effect, or depensation, implies positive association between per capita population growth rate and population size at low abundances, thereby lowering growth ability of sparse populations. This can have far-reaching consequences on population recovery ability and colonization success. In the context of marine fishes, there is a widespread perception that Allee effects are rare or non-existent. However, studies that have failed to detect Allee effects in marine fishes have suffered from several fundamental methodological and data limitations. In the present study, we challenge the prevailing perception about the rarity of Allee effects by analysing nine populations of …

0106 biological sciencesPopulation DynamicsAtlantic herringBiologyModels Biological010603 evolutionary biology01 natural sciencesPopulation densityGeneral Biochemistry Genetics and Molecular BiologycompensationDepensationsymbols.namesakePer capitaAnimalsPopulation growth14. Life underwaterClupea harengusPopulation GrowthGeneral Environmental ScienceAllee effectlow-abundance dynamicsPopulation DensityModels StatisticalEcologyGeneral Immunology and MicrobiologyEcology010604 marine biology & hydrobiologyModel selectionPopulation sizestock–recruitment relationshipFishesBayes TheoremGeneral MedicineData availabilitydepensationsymbolsta1181General Agricultural and Biological SciencesProceedings of the Royal Society B: Biological Sciences
researchProduct

Town population size and structuring into villages and households drive infectious disease risks in pre-healthcare Finland

2021

Social life is often considered to cost in terms of increased parasite or pathogen risk. However, evidence for this in the wild remains equivocal, possibly because populations and social groups are often structured, which affects the local transmission and extinction of diseases. We test how the structuring of towns into villages and households influenced the risk of dying from three easily diagnosable infectious diseases—smallpox, pertussis and measles—using a novel dataset covering almost all of Finland in the pre-healthcare era (1800–1850). Consistent with previous results, the risk of dying from all three diseases increased with the local population size. However, the division of towns …

0106 biological sciencesPopulationDiseaseCommunicable Diseases010603 evolutionary biology01 natural sciencesMeaslesGeneral Biochemistry Genetics and Molecular BiologySocial group03 medical and health sciencesmedicineHumansSmallpoxCitieseducationFinland030304 developmental biologyGeneral Environmental SciencePopulation Density0303 health scienceseducation.field_of_studyEcologyGeneral Immunology and MicrobiologyTransmission (medicine)Population sizeGeneral Medicinemedicine.diseaseGeographyInfectious disease (medical specialty)General Agricultural and Biological SciencesDelivery of Health CareDemographyProceedings of the Royal Society B: Biological Sciences
researchProduct

Obtaining antioxidants and natural preservatives from food by-products through fermentation: A review

2021

Industrial food waste has potential for generating income from high-added-value compounds through fermentation. Solid-state fermentation is promising to obtain a high yield of bioactive compounds while requiring less water for the microorganism’s growth. A number of scientific studies evinced an increase in flavonoids or phenolics from fruit or vegetable waste and bioactive peptides from cereal processing residues and whey, a major waste of the dairy industry. Livestock, fish, or shellfish processing by-products (skin, viscera, fish scales, seabass colon, shrimp waste) also has the possibility of generating antioxidant peptides, hydrolysates, or compounds through fermentation. These bioacti…

0106 biological sciencesPreservativeAntioxidantantioxidantMicroorganismmedicine.medical_treatmentFermentation industries. Beverages. AlcoholFood spoilagePlant ScienceAntifungal01 natural sciencesBiochemistry Genetics and Molecular Biology (miscellaneous)Hydrolysate0404 agricultural biotechnology010608 biotechnologymedicineBioreactorFood sciencefermentationFood by-productsTP500-660Chemistryfood and beverages04 agricultural and veterinary sciences040401 food scienceFood wasteFermentationFermentationfood by-productsAntioxidantantifungalFood ScienceFermentation
researchProduct

Next-generation biological control

2020

Biological control is widely successful at controlling pests, but effective biocontrol agents are now more difficult to import from countries of origin due to more restrictive international trade laws (the Nagoya Protocol). Coupled with increasing demand, the efficacy of existing and new biocontrol agents needs to be improved with genetic and genomic approaches. Although they have been underutilised in the past, application of genetic and genomic techniques is becoming more feasible from both technological and economic perspectives. We review current methods and provide a framework for using them. First, it is necessary to identify which biocontrol trait to select and in what direction. Nex…

0106 biological sciencesProteomicsH10 Pests of plantsInternationalityComputer science[SDV]Life Sciences [q-bio]Laboratory of VirologySequence assemblybiological controlmicrobiome01 natural sciencesGenome editinggeneticsNagoya ProtocolLaboratory of EntomologyCYTOPLASMIC INCOMPATIBILITY2. Zero hunger0303 health sciencesQUANTITATIVE TRAIT LOCICommercefood and beveragesCONTROL AGENTSPE&RCBiosystematiekNASONIA-VITRIPENNISGUT CONTENT-ANALYSIS[SDE]Environmental SciencesTraitinsect breedingAXYRIDIS COLEOPTERA-COCCINELLIDAEOriginal ArticleLaboratory of GeneticsLIFE-HISTORY TRAITSGeneral Agricultural and Biological SciencesGenomicsContext (language use)Computational biology[SDV.BID]Life Sciences [q-bio]/Biodiversityartificial selectionQuantitative trait locusAnimal Breeding and GenomicsLaboratorium voor Erfelijkheidsleer010603 evolutionary biologyGeneral Biochemistry Genetics and Molecular BiologyLaboratorium voor Virologiemodelling03 medical and health sciencesgenomics[SDV.BV]Life Sciences [q-bio]/Vegetal BiologyFokkerij en GenomicaPARASITOID WASPSelection (genetic algorithm)modelling.030304 developmental biologySEX DETERMINATIONOriginal ArticlesLaboratorium voor EntomologieWIASgenome assemblyBiosystematicsEPSartificial selection biological control genetics genome assembly genomics insect breeding microbiome modellingBiological Reviews
researchProduct

A new ursane-type triterpene oxoglucopyranoside from Crossopteryx febrifuga.

2019

Abstract A new saponin, 3-O-β-d-3-oxo-glucopyranosyl-ursa-12,20(30)-diene-27,28-dioic acid (1), was isolated from the methanol extract of stem bark of Crossopteryx febrifuga together with the known 3β-d-glucopyranosyl-ursa-12,20(30)-diene-27,28-dioic acid (2), shanzhiside methyl ester (3), shanzhiside (4), β-sitosterol (5), β-sitosterol-3-O-β-d-glucopyranoside (6), ursa-12,20(30)-diene-27,28-dioic acid (7), hederagenin (8), and oleanolic acid (9). The structures were established by comprehensive interpretation of their spectral data 1D- (1H and 13C), 2D-NMR (1H-1H COSY, HMQC, HMBC), spectroscopic, and electrospray ionisation time-of-flight mass spectrometry analysis. The isolated compounds …

0106 biological sciencesProton Magnetic Resonance SpectroscopySaponinRubiaceaeMicrobial Sensitivity Testsmedicine.disease_cause01 natural sciencesGeneral Biochemistry Genetics and Molecular BiologyEnterococcus faecalischemistry.chemical_compoundMinimum inhibitory concentrationTriterpeneGlucosidesmedicineCarbohydrate ConformationCarbon-13 Magnetic Resonance SpectroscopyOleanolic acidchemistry.chemical_classificationChromatographybiologyBacteriaChemistrybiology.organism_classificationTriterpenes0104 chemical sciences010404 medicinal & biomolecular chemistryHederageninStaphylococcus aureusAntibacterial activity010606 plant biology & botanyZeitschrift fur Naturforschung. C, Journal of biosciences
researchProduct

Active Wild Food Practices among Culturally Diverse Groups in the 21st Century across Latgale, Latvia

2021

Simple Summary A study in the bordering region of Latvia took place in order to investigate wild plant food uses. In total 72 interviewees reported food uses. The most represented uses of recorded plants were recreational tea; for jam; as snacks and soup; and drink. Interviewees also reported loss of foraging practice due to the habitat change as for example in case of caraway and chamomile. The results indicated that part of the reason for the main use of wild plants were linked to diet diversification. Abstract Local ecological knowledge (LEK), including but not limited to the use of wild food plants, plays a large role in sustainable natural resource management schemes, primarily due to …

0106 biological sciencesQH301-705.5BiodiversityContext (language use)Diversification (marketing strategy)Biology01 natural sciencesGeneral Biochemistry Genetics and Molecular BiologyArticleSettore BIO/01 - Botanica GeneraleforagingCultural diversityBiology (General)Natural resource managementSocioeconomicsnatural resourcesRecreationGeneral Immunology and Microbiologyfood and beverageswild food plantslocal ecological knowledgeNatural resourceLatvia0104 chemical sciencesLocal community010404 medicinal & biomolecular chemistryGeneral Agricultural and Biological SciencesForaging; Latvia; Local ecological knowledge; Natural resources; Wild food plants010606 plant biology & botanyBiology
researchProduct

First data on microflora of loggerhead sea turtle (Caretta caretta) nests from the coastlines of Sicily (Italy)

2020

ABSTRACT Caretta caretta is threatened by many dangers in the Mediterranean basin, but most are human-related. The purposes of this research were: (i) to investigate microflora in samples from six loggerhead sea turtle nests located on the Sicilian coast and (ii) to understand microbial diversity associated with nests, with particular attention to bacteria and fungi involved in failed hatchings. During the 2016 and 2018 summers, 456 eggs and seven dead hatchling from six nests were collected. We performed bacteriological and mycological analyses on 88 egg samples and seven dead hatchlings, allowing us to isolate: Fusarium spp. (80.6%), Aeromonas hydrophila (55.6%), Aspergillus spp. (27.2%) …

0106 biological sciencesQH301-705.5ZygoteScienceMicrofloraZoology010603 evolutionary biology01 natural sciencesLoggerhead sea turtleMediterranean BasinGeneral Biochemistry Genetics and Molecular BiologyNesting Behaviorlaw.invention03 medical and health sciencesMediterranean seaFusariumlawSea turtle eggsMediterranean SeaAnimalsBiology (General)Internal transcribed spacerTurtle (robot)SicilyHatchling030304 developmental biologyCaretta caretta0303 health sciencesbiologyHatchingMicrobiotaQbiology.organism_classificationAeromonas hydrophilaTurtlesCitrobacter freundiiAspergillusThreatened speciesGeneral Agricultural and Biological SciencesResearch ArticleBiology Open
researchProduct

Arabidopsis SGS2 and SGS3 genes are required for posttranscriptional gene silencing and natural virus resistance.

2000

AbstractPosttranscriptional gene silencing (PTGS) in plants results from the degradation of mRNAs and shows phenomenological similarities with quelling in fungi and RNAi in animals. Here, we report the isolation of sgs2 and sgs3 Arabidopsis mutants impaired in PTGS. We establish a mechanistic link between PTGS, quelling, and RNAi since the Arabidopsis SGS2 protein is similar to an RNA-dependent RNA polymerase like N. crassa QDE-1, controlling quelling, and C. elegans EGO-1, controlling RNAi. In contrast, SGS3 shows no significant similarity with any known or putative protein, thus defining a specific step of PTGS in plants. Both sgs2 and sgs3 mutants show enhanced susceptibility to virus, d…

0106 biological sciencesRNA-induced transcriptional silencingDNA PlantRNA-induced silencing complexTrans-acting siRNAMolecular Sequence DataPotyvirusArabidopsisRNA-dependent RNA polymerase[SDV.BC]Life Sciences [q-bio]/Cellular BiologyGenes Plant01 natural sciencesCucumovirusGeneral Biochemistry Genetics and Molecular Biology03 medical and health sciencesSolanum lycopersicumRNA interferenceArabidopsisGene expressionGene silencingAmino Acid SequenceGene SilencingCloning MolecularRNA Processing Post-Transcriptional[SDV.BC] Life Sciences [q-bio]/Cellular BiologyComputingMilieux_MISCELLANEOUS030304 developmental biologyPlant DiseasesPlant ProteinsGenetics0303 health sciencesbiologyBase SequenceBiochemistry Genetics and Molecular Biology(all)Arabidopsis ProteinsfungiTobamovirusChromosome MappingGENETIQUEbiology.organism_classificationRNA-Dependent RNA PolymeraseMutagenesis010606 plant biology & botanyCell
researchProduct

Gene flow relates to evolutionary divergence among populations at the range margin

2020

Background Morphological differentiation between populations resulting from local adaptations to environmental conditions is likely to be more pronounced in populations with increasing genetic isolation. In a previous study a positive clinal variation in body size was observed in isolated Roesel’s bush-cricket, Metrioptera roeselii, populations, but were absent from populations within a continuous distribution at the same latitudinal range. This observational study inferred that there was a phenotypic effect of gene flow on climate-induced selection in this species. Methods To disentangle genetic versus environmental drivers of population differences in morphology, we measured the size of …

0106 biological sciencesRange (biology)Climatelcsh:MedicineBody sizeBiology010603 evolutionary biology01 natural sciencesGeneral Biochemistry Genetics and Molecular BiologyGene flowEvolutionsbiologi03 medical and health sciencesAdaptive divergenceMargin (machine learning)GeneticsGenetikGenetic isolation030304 developmental biologyEvolutionary Biology0303 health sciencesEcologyMorphological differentiationGeneral Neurosciencelcsh:RVDP::Matematikk og Naturvitenskap: 400Body sizeGeneral MedicineEvolutionary StudiesEvolutionary biologyOrthopteraEvolutionary divergenceGeneral Agricultural and Biological SciencesEntomologyZoologyGenetic isolatePeerJ
researchProduct